Central nervous system mycoses: The challenges

Central nervous system mycoses: the challenges.

[mycoses of the Central Nervous System].

The incidence of mycotic infections in the CNS has increased even outside those groups of patients with increased risk (AIDS, drug-addicts, etc.). These cases are secondary complications of other basic diseases favored by the influence of modern drug treatment and misinterpretation of modern diagnostic findings (radiology). A more frequent control of mycotic infections even in routine controls ...

Epidemiology of central nervous system mycoses.

Fungal infections of the central nervous system (CNS) were considered rare until the 1970s. This is no longer true in recent years due to widespread use of corticosteroids, cytotoxic drugs and antibiotics. Immunocompromised patients with underlying malignancy organ transplantations and acquired immune deficiency syndrome are all candidates for acquiring fungal infections either in meninges or b...

ADENOSINE IN THE CENTRAL NERVOUS SYSTEM

Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...

Diagnostic Challenges of Central Nervous System Tuberculosis

Central nervous system tuberculosis (TB) was identified in 20 cases of unexplained encephalitis referred to the California Encephalitis Project. Atypical features (encephalitic symptoms, rapid onset, age) and diagnostic challenges (insensitive cerebrospinal fluid [CSF] TB PCR result, elevated CSF glucose levels in patients with diabetes, negative result for tuberculin skin test) complicated dia...